Could anyone having this issue please try build 3584 and let me know if it makes any difference.
Also, have a play with the new option -> Audio Engine -> Thread Affinity Mode -> Disabled/Preferred/Forced and let me know if that makes any difference.
For details about these options, see this post.
Explanation:
From what’s been described above it seems as though Windows is scheduling some of Cantabile’s core audio threads to run on the same processor core. I’ve personally never seen this, but that’s sure what it sounds like.
In an attempt to solve this, Cantabile can now specify “this thread” should run on “this processor” via the Thread Affinity mode options. See the above linked post for more about the different affinity modes - but basically either “Preferred” or “Forces” should (hopefully) resolve the issue.
Brad