I’m not @brad, but I still checked your log file. I see that your audio interface was initialized at 48 kHz and I see that you have an OP-X in your setup. Some older versions of the OP-X Pro (before V1.2.1) used to be unable to deal with 48 kHz - newer version have apparently fixed this.
Could it be that only your OP-X was detuned and all your other instruments were in tune - this could have given the impression of “floating detune”. The newest version of OP-X should be OK with 48 kHz
Or maybe there’s another plugin in your setup that can’t deal with 48 kHz. Are you running your setup in 44.1 kHz now? Maybe that’s a reason for everything playing nice now…
Could you tell us a bit more about your audio interface and its configuration?