I have a problem with my Focusrite Scarlett 2i4 where it is definitely plugged in, but not recognised (even in Device Manager), until you unplug it while the computer is on and replug it - tricky as it is buried in my rack. I am thinking of a small extension lead so I can disconnect/reconnect without having to pull the rack to bits.
Anyway, I soon found the pattern that causes this issue for me. It is doing Windows updates and letting the computer restart after the update.
If I update and shutdown, cut the power to the rack, restore it and then restart, then it is fine.
Not sure why, but it works. It may or may not help you, but worth pointing out.