Certainly not a show-stopper, but …
In the Routing Wiring view, If I have a route from an input port directly to an output port that is exactly at the same vertical position as the input port, I cannot select that route. If I move either the input port or the output port up or down slightly, I can select the route as normal.
I have not done extensive testing with this (like inserting plugins, etc).
Performer, Build 3672 Win10x64