Yes, after you install the waveshell that goes with all Waves plugs you can run all Waves plugins in Cantabile. Out of curiosity what type of noise are you fighting with? A noise gate is also a solution because it will effectively mute or “Gate” the mic until you talk into it and turn the gate back on when you don’t for a period of time that you specify. I use the TrackGate from DMG Audio but there are many others both free and pay.
Many years ago I used a noise reduction program called “SoundSoap”. I used it for removing noise from vinyl records and cassette tapes and camcorder motor noise. It might be worth a try for your computer background noise. It’s expensive to buy, but is free to try out.