I have 2 of these - one at home, and one in the rack. Like you, I plug the audio interface directly into the PC, and everything else into this hub. I also have a MIdi Expression plugged into this hub as well as a Roland keyboard, and various other devices. All works well. I’d recommend it.
I actually run 5 separate USB cables as well as 12v for the piano, HDMI for the portable monitor, and stereo audio out from the keyboard from the rack to my keyboard stand. All cable lengths are 5m. I preferred to do this rather than bring the USB hub and power to the stand. These are all loomed together in wrap, and colour coded so only take a few seconds to plug in. I’ve posted a pic of my rack in the “show rig” thread.
A couple of things I’ve found along the way.
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My PC - a Gigabyte Brix-s Kaby Lake has both usb 3.0 (Intel chipset) and 3.1 (ASMedia chipset). USB 2 devices work fine when plugged into the Intel port but not when directly into the ASMedia port. USB 2 devices do work when plugged in to the ASMedia socket via this hub! This sems to be a known issue with 3.1 chipsets.
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Most hubs (including this one) seem to cascade their ports in groups of 4. That means ports 1 to 3 will be provided by one “chip”. Ports 4 to 7 will be driven from a 2nd “chip” which is connected internally into the 4th port of chip 1. And so on. With a 13 port hub, that means 4 cascades which is the maximum you can have. The hub must therefore be plugged directly into a PC usb socket for all the ports to work. The PC must have a host USB socket not an internal hub. I have had issues before (not on this hub) where devices plugged into higher port numbers aren’t reliable. I diagnosed this with USBview software.